Considering Decriminalization: NJ Marijuana Arrests

6/20/2011 – NJ Assemblyman Reed Gusciora is expected to introduce a bill this week to decriminalize the possession of up to 14 grams of marijuana by adults. A look at the Uniform Crime Report from the NJ State Police reveals some striking statistics for marijuana arrests. The 2009 report contains the most recent published data available, although preliminary data on 2010 points to an increase for cannabis violations.

In 2009 the Garden State arrested 26, 254 people for marijuana. Eight-five percent of the arrests (22, 439) were for possession of less than 50 grams. Currently, adults caught with anything from a joint to two-ounces are treated the same way; with a custodial arrest and a criminal prosecution.

In 2009 New Jersey performed more arrests for marijuana than for all other drugs combined. Fifty-six percent of all drug possession arrests were for marijuana.

The same year saw 3,815 arrests for Sale/Manufacture of marijuana. This is compared to 8,128 arrests for sale/manufacture of cocaine or opium products in 2009. Yet fewer NJ residents were arrested in possession of cocaine or opiates (14,609) than for marijuana (22,439).

The conclusion that could be drawn that enforcement of cannabis prohibition laws in New Jersey is focused on the individual user rather than those selling. This is different compared to other drugs.

Some additional information from the NJ UCR

– Forty-two percent of persons arrested for drug abuse violations were under the age of 21.

– Males accounted for 81 percent and females 19 percent of the arrests.

– Fifty-four percent of total persons arrested in 2009 were white, 45 percent were black and 1 percent were other races.

– The Hispanic ethnic origin accounted for 14 percent of the arrests and 86 were non-Hispanic.

Fourteen US states allow a civil citation to be issued at the point of encounter with police.  A nominal fine is levied at a later time and the offense is treated similar to a traffic violation for speeding. The decrim states on the east coast include: Maine, New York, Massachusetts and Connecticut.

Chris Goldstein is a respected marijuana reform advocate. As a writer and radio broadcaster he has been covering cannabis news for over a decade. Questions?  [email protected]


Cannabis and PTSD Clinical Trials Announced

The International Association for Cannabinoid Medicine published a bulletin highlighting the preliminary results from an observational clinical trial studying the effects of Cannabis on post traumatic stress disorder (PTSD).

“According to an observational study by scientists of MaReNa Diagnostic and Consulting Center in Bat-Yam, Israel, presented at the Cannabinoid Conference 2011 in Bonn, Germany, the use of cannabis may improve symptoms of posttraumatic stress disorder. As a part of their routine consulting work, they assessed the mental condition of 79 adult PTSD patients, who applied to the Ministry of Health in order to obtain a license for the medical use of cannabis. Only part of them (about 50 per cent) got cannabis licenses and constitutes the study group. They were followed for a period of about two years.”

One of the oldest known medical uses for Cannabis is in the treatment of psychiatric disorders, as described in the ancient Ayurvedic texts from India (Russo 2005). This ancient medicinal claim is proving itself true through recent scientific studies. Scientists studying fear conditioning in animals discovered that the CB1 receptor is necessary for the extinction of adverse memories (Marsciano 2002). Researchers studied mice that are genetically bred without the CB1 receptors. These mice without CB1 receptors have an impaired ability to extinguish fear. Scientists have also tried using the drug Rimonbandt, which blocks the CB1 receptor and seen similar results (Lutz 2007).

The CB1 receptor is the most abundant protein in the human protein, and anyone who has activated this receptor with THC can tell you about its effect on memory. This memory impairment associated with Cannabis can be harnessed for medical uses.

The CB1 receptor is part of the endocannabinoid system (ECS). The ECS is a natural part of our body and among many things it controls things such as eating, sleeping relaxing, and memory. Conceptually, by adding THC to the brain, the ECS is turned on and begins to do its work. THC from the Cannabis plant and our body’s endocannabinoids may control the extinction of adverse memories by acting through the CB1 receptor. Adverse memories underlie or cause many anxiety disorders such as PTSD. You don’t have to be a veteran to receive relief from Cannabis for a psychiatric disorder. The extinction of adverse memories through the CB1 receptor is emerging as a universal mechanism in the brain.

Despite a vast amount of scientific information on the effect of cannabinoids on memory, the first clinical trial on Cannabis and PTSD is yet to be completed. This clinical trial is an obvious next step that will test the effect of CB1 receptor stimulation on adapting to fear. This is something scientists have not been successful at studying; researchers have only been approved to study the effect of CB1 receptors on anxiety disorders indirectly through genetically altered mice and by blocking the receptor.

Cannabis and cannabinoids may offer a benefit in the treatment of anxiety disorders, such as phobias (fears) or PTSD, and the pain that is often associated with them. The implications of the current scientific data suggest that Cannabis and cannabinoids can treat a wide range of anxiety orders. If you are feeling nervous about the speculation of using Cannabis to treat anxiety disorders, just remember the title from Nature magazine’s 2002 article, “Never Fear, Cannabinoids are Here (Sah, 2002).”

 
Bibliography

Lutz, B. (2007). The Endocannabinoid System and Extinction Learning. Molecuar Neurobiology, 36:92-101.

Marsciano, G. (2002). The Endogenous Cannabioid System Controls the Extinction of Adverse Memories. Nature, 530-534.

Russo, E. (2005). Cannabis in Inida: ancient lore and modern medicine. In R. Mechoulam, Cannabinoids as Therpeutics.

Birkhäuser Verlag/Switzerland. Sah, P. (2002). Never Fear, Cannabinoids are Here. Nature, 488-489.

Jahan Marcu is currently investigating the pharmacology of cannabinoid receptors. He was working at the California Pacific Medical Center Research Institute when exciting discoveries were made showing enhanced anti-cancer effects with THC and CBD from the Cannabis plant. The findings were published in the Journal of Molecular Cancer Therapeutics. In 2009 he received the Billy Martin Award from the International Cannabinoid Research Society (ICRS). Jahan is currently the vice-chair the Medical and Scientific Advisory Board at Americans for Safe Access (ASA). Questions?   Contact    [email protected]

DISCLAIMER: The views and opinions expressed are those of the author and do not necessarily represent any University, business or affiliates. While the information provided in this blog is from published scientific studies it is not intended to diagnose or treat any disease.

CONSTITUTIONAL LAWSUIT FILED OVER FAILED NJ MEDICAL MARIJUANA PROGRAM

FOR IMMEDIATE RELEASE – April 4, 2012

ATTORNEYS WILLIAM H. BUCKMAN AND ANNE M. DAVIS

CONTACT: Anne Davis Esq. 732 477 4700, William Buckman Esq. 856 608 9797 or Chris Goldstein 267 702 3731

CONSTITUTIONAL LAWSUIT FILED OVER FAILED NJ MEDICAL MARIJUANA PROGRAM

Trenton- Today a lawsuit was filed against the State of New Jersey over the failure to implement the Compassionate Use Medical Marijuana Act. Named in the suit are the Department of Health and Senior Services (DHSS) Commissioner Mary O’Dowd and the newly appointed director of the Medicinal Marijuana Program John O’Brien.

Civil rights attorneys William H. Buckman of Moorestown and Anne M. Davis of Brick brought the suit on behalf of a New Jersey medical patient who would qualify for cannabis access. The suit also represents one of the few medical doctors who have registered with NJ to recommend medical marijuana.

The compassionate use law was passed in January 2010 with a six-month implementation timeline. But since 2010 a series of politically motivated regulatory, legislative and bureaucratic delays have kept the program from operating at all. None of the six approved Alternative Treatment Centers have been fully permitted by DHSS to open.

“We represent a patient who suffered actual damages as a result of these delays,” said Anne Davis, “He cannot utilize the cannabis because New Jersey’s lack of a working program means he could lose his disability pension if he tested positive for cannabis.”

Davis continued, “Our neighbors with AIDS, cancer, MS and the worst of medical conditions have testified before the legislature and changed the law. Now, patients and doctors have to go to court to win the rights that they should have already been afforded.”

The lawsuit gathers more than two years of facts demonstrating that those in charge of the implementation process for New Jersey’s medical marijuana program have been unable or unwilling to put the law into place.

“Today we are filing suit to require the DHHS to do what every other citizen must do – follow the law,” said William Buckman, “We are also insisting that pursuant to the legislature’s will, sick people have access to medical marijuana without fear of arrest.”

For more information about this advisory please contact Anne M. Davis Esq. 732 477 4700, William H. Buckman Esq. 856 608 9797 or Chris Goldstein 267 702 3731

Cannabis College Crackdown and Other New World Orders

Today, I woke up to find that the Supreme Court of the United States ruled by a 5-to-4 vote that officials may strip-search people arrested for any offense,  however minor, before admitting them to jails even if the officials have no reason to suspect the presence of contraband.

Now, I’m no Constitutional know-it-all by any stretch of the imagination, but I seem to recall something called, oh what is it…oh that’s right: The Fourth Amendment, which goes a little something like this:

The right of the people to be secure in their persons, houses,  papers, and effects, against unreasonable searches and seizures, shall  not be violated, and no warrants shall issue, but upon probable cause,  supported by oath or affirmation, and particularly describing the place  to be searched, and the persons or things to be seized.

Interesting. The HIGHEST COURT IN THE LAND just rolled back the Fourth Amendment…because it can.

But then again, that pesky Constitution as well as laws that the public has resoundingly voted in favor of don’t seem to stop public officials from doing whatever the hell they want.

Take a look at Oaksterdam College, which the DEA and IRS raided on Monday, shutting down the cannabis industry trade school while carrying out a federal search warrant. And guess what? They don’t have to explain what they’re doing to anyone because all of the paperwork is “under seal” other than to confirm it is part of a (insert sarcastic laughter) “ongoing joint investigation.”

Now, Oakland doesn’t have a lot of money. But it does have a lot of crime. Which coincidentally occurred during this needless raid. In a different part of the city, seven people at Oikos Christian University were lined up and gunned down by a former student.

We will probably never know whether the limited police force raiding a successful trade school could have actually fought real crime only miles away. (You know, do that “life saving” thing that we pay them to do.)

Richard Lee, who runs the “cannabis college”, was detained then released. His home was raided by  agents with guns (because this wheelchair bound activist is such a threat. Where’s your raid on Wall Street?), according to Dale Sky Jones,  chancellor of  Oaksterdam. Four marijuana nursery workers were detained at Oaksterdam. No arrests were made.

Don Duncan of Americans for Safe Access writes:

This is a grave injustice against local patients and a slap in the face for a city that has led the state in sensible regulations for medical cannabis. Americans for Safe Access (ASA) helped to mobilize protesters this morning, and is working to frame this story in the media right now. We wish we did not need an Emergency Response Campaign but today’s events show that we still do.

So whose to blame for all of this needless militaristic force that descended upon a legitimate trade college going about their business?

From left, U.S. Attorney Benjamin Wagner (Eastern District), U.S. Attorney Laura Duffy (Southern District), U.S. Attorney Melinda Haag (Northern District) and U.S. Attorney Andre Birotte (Central District)

These four attorneys stated in October that they would aggressively  prosecute many marijuana dispensaries as profit-making criminal  enterprises. Staying true to their word, three dispensaries in San Francisco, one in  Marin County and 50 in Sacramento have closed under  pressure, in addition to about 150 others throughout the state of California.

This team of legal vigilantes have made it their mission to defy their constituents’ wishes under the guise of “protecting the children”, whose schools may be too close to dispensaries. (Note: The “protecting the children” defense is almost always a cloak for politically motivated agenda.)

“Its a total waste of federal resources,” Stephanie Tucker,  spokesperson for the San Francisco medical cannabis task force, told The Huffington Post. “They’re attacking a peaceful, regulated community, and  it’s wasting money. Shame on them.”

Indeed shame on them. And shame on all of the legislators who have taken it upon themselves to rewrite The Constitution and hoist their own self-created political agenda upon a public that voted them into office.

God bless America…it’s going to need all the help it can get.

Beth Mann is a popular blogger and writer for Open Salon and Salon. She is also an accomplished artist with over 15 years of experience, as well as the president of Hot Buttered Media. She currently resides at the Jersey shore where she can be found surfing or singing karaoke at a local dive bar.

Contact: maryjane {at } freedomisgreen.com

Contributions by:

Jahan Marcu is currently investigating the pharmacology of cannabinoid receptors. He was working at the California Pacific Medical Center Research Institute when exciting discoveries were made showing enhanced anti-cancer effects with THC and CBD from the Cannabis plant. The findings were published in the Journal of Molecular Cancer Therapeutics. In 2009 he received the Billy Martin Award from the International Cannabinoid Research Society (ICRS). Jahan is currently the vice-chair the Medical and Scientific Advisory Board at Americans for Safe Access (ASA). Questions? Contact [email protected]

DISCLAIMER: The views and opinions expressed are those of the author and do not necessarily represent any University, business or affiliates. While the information provided in this blog is from published scientific studies it is not intended to diagnose or treat any disease.

CORRECTIONS: NYC Rally, East Coast Gets Serious

Sometimes my typing get ahead of me…

Two important corrections to the blog: Rally in NYC: Marijuana is Safer for St. Pat’s

1-     State of New York decriminalized marijuana in 1977 not 1979.

2-     Marijuana in Public View is not a municipal code as stated in the blog.

Professor Harry Levine clarified today: “New York State Criminal Law 221.10 specifies that possession is a misdemeanor if it is ‘burning or open to public view.’  The phrase ‘MPV’ was invented by Andy Golub, a researcher, and as far as I know has never been used by the police or courts in New York.”

Further there are no specific municipal codes for marijuana in NYC but police practice has changed accounting for the 50,000 annual pot arrests despite decriminalization.

Corrections to East Coast gets serious about marijuana:

1- Omitted the bill active in North Carolina – that has been added.

3-     Finally in the same piece I did not highlight the strong medical cannabis caregiver network that exists in Maine. Added a link to the sixth paragraph.

Please send any questions or corrections to chris { at } freedomisgreen.com.

Thanks for your feedback!

Chris Goldstein

Cannabis Laboratories: The Testing Landscape in America

Gas chromatography equipment – WikiMedia Commons

[Note – This guest blog was submitted by Samantha Miller of Pure Analytics.]

5/23/2011 – The testing of commercially available cannabis for cannabinoid profile and potency is becoming more prevalent. This is important information for patients and dispensaries who increasingly seek out these profiles.  The availability of cannabis testing promotes better access to medically important cannabis options such as CBD-rich cannabis, through identification. Laboratory testing is also key for strategic breeding programs and promotes the overall legitimization of cannabis for therapeutic use.  Right now the cannabis testing industry is unregulated.

An easy-to-read cannabinoid profile helps medical cannabis patients choose the strains that best suit the therapy requirements for their ailment.  The cannabinoid potency information provides guidance in determining an individual’s dosage through self-experimentation, often called “self-titration”.  Reliable cannabinoid profiles also support the ability for patients to achieve a repeat of therapeutic benefits without experiencing unwanted intoxication.

Today, because of increased awareness, patients are more interested in consuming cannabinoids other than THC.  Potency testing can play an important role in promoting knowledge and availability of non-THC options. First, through the identification of cannabis strains and cannabis products with medically important non-THC cannabinoids such as CBD. These cannot be detected by visual or other sensory means such as smell.

Cannabidiol

Secondly, through the use of lab testing to identify specific plants, they can be used in breeding programs designed to develop and isolate plants that are high in CBD, CBG or some other cannabinoid of interest. Laboratory testing can be used to identify the precise cannabinoid profile of plants to determine genetic traits that promote the development of non-THC dominant cannabis. Then cross-breeding can be undertaken based upon our understanding of the genetics of the expression of those cannabinoids.

The medical cannabis industry has the great potential to provide enhanced legitimacy with reliable laboratory testing.  One such area concerns human use and consumption where testing provides information not just on potency but assures the absence of harmful pesticides.

Cannabis laboratories are also generating a rapidly growing body of data. The development of this new database can be used to support the characterization of cannabis as a medicinal plant in the effort to re-schedule its classification in the federal Controlled Substances Act .

The prevalence of cannabis testing is certainly on the rise. The emerging cannabis testing industry is a dynamic environment driven largely by economic influences.  In the last decade the decision to test has largely been driven by weighing the costs and the benefits from a marketing perspective.

Today, a very competitive market exists for medicinal cannabis in California and other states.  New cannabis testing laboratories are starting-up on a frequent basis to serve a perceived economic opportunity.  Some activist groups have raised concerns over the nature of segments of the new cannabis lab industry.

There are non-qualified service providers, “dry labs” who outsource all analysis or even fabricate results. There are also unscrupulous laboratory instrument companies that are raising concerns by marketing expensive equipment to medical cannabis collectives to attempt their own testing.  As a response, patients and collectives are asking important questions about the reliability of the results.

The is no regulatory oversight for cannabis testing that compared to what already exists in most other fee-for-service analytical chemistry industries.  This makes the water a bit murkier when looking for a reputable and qualified service provider for cannabis testing services. In an environment where providing analytical results is regulated (drinking water, soil and food) a customer can simply choose from a list of service providers who have all been certified to the same set of standards for accuracy and precision in their work.

A regulated environment offers an agreed upon well-tested methodology.  There also would exist an agreed upon set of requirements for quality control of ongoing work such as requirements for the frequency and acceptance criteria of the calibration of equipment. In the absence of regulation these aspects of analysis, even providing results to a customer, can happen under widely varying circumstances.

The importance of a consistency for method validation and ongoing quality control become clear when you consider the multiple factors that affect accuracy. For example, the method of sampling at the dispensary or cultivator level can have serious influences on lab results. A single sample that is representative of the entire unit of plant material must be submitted for analysis to obtain a result that accounts for the variation within that unit.

The second tier of cannabis sampling, which occurs at the level of the laboratory, also has an influence. This is where the cannabis sample is prepared and extracted for analysis.  The process involves the use of precision weighing and volumetric measurement equipment which must be calibrated and verified at regular intervals.  The proper calibration of analytical equipment is also imperative to the production of reliable and repeatable data.  Key factors include the use of certified standards that have been third-party tested and certified for purity and concentration.

Proper maintenance of equipment is a final important element for ensuring that the results provided to the customer are delivered with the highest confidence level.

The good news is that in the absence of regulated oversight, cooperative work between existing labs to perform side-by-side testing of cannabis samples can provide an important element to fostering confidence at the consumer level.

A very important aspect of cannabis laboratory practice that varies between service providers is the choice of analytical equipment.  In general, the choice of equipment centers on the use of gas chromatography (GC) versus liquid chromatography (HPLC) for cannabinoid analysis.  As in every industry there is often an effort to promote what differentiates a service as what makes it better than another. In the case of GC versus HPLC some service providers have attempted to position their equipment as superior to another.  The truth is that types of equipment can provide accurate, reliable data for cannabinoid analysis.

It is not as simple as the hardware.  A key factor to consider when reviewing the appropriate equipment for a given analysis is making sure the correct type of detector is being used. This is especially important for gas chromatograph analysis of cannabinoids.  In the case of GC there are options of FID (flame ionization detector), MS (mass spectrometer) and TCD (thermal conductivity detector).  Gas chromatograph units equipped with both FID and MS detectors have been shown to provide reliable results.

The TCD detectors commonly sold by instrument companies to dispensaries are not a good choice.  One reason is that the results are often influenced by the interference of other cannabinoids present aside from THC, CBD and CBN.

There are also a segment of cannabis laboratory service providers utilizing results from TLC or Thin Layer Chromatography, often referred to as “test strips.”  In some of these cases these test strips are promoted as being able to provide accurate potency results for cannabis.  In general, without specialized equipment, test strips are only viable for use to tell whether or not certain cannabinoids are present, but not how much is present (e.g. potency).

The most appropriate method for cannabinoid analysis is also determined by the type of sample being analyzed.  In today’s cannabis industry, the vast majority of samples submitted to laboratories for testing consist of processed, dried flowers intended for vaporization or combustion.  Testing by GC-FID, GC-MS or LC is appropriate for these samples when looking to identify cannabinoid profile and potency level.

But, for those samples that may contain the un-activated or “acid” form of THC and CBD when consumed, analysis by liquid chromatography is more appropriate.  Gas chromatography (GC) is unable to detect if these “acid” forms remain present, a consideration that is important when trying to consider dosage of an edible or tincture ingestible.  This is because analysis by GC essentially simulates what happens when cannabis is vaporized or combusted.  The acid forms of THC and CBD are converted to the active forms when heated. Heating is a part of analysis by GC.  This is important because many tincture and edible makers do not activate their cannabinoids through adequate heating of their products, leaving some cannabinoid in the “acid” form.

For a summary on the similarities and differences between GC and LC equipment see table 1.

Table 1.  Comparison of Gas Chromatography and High Performance Liquid Chromatography

Gas Chromatography Liquid Chromatography
A low pressure stream of gas helps move the compounds to the detector A high pressure stream of solvent helps move the compounds to the detector
The system is heated during analysis The system is usually at ambient temperature during analysis
Detects total available THC, CBD and CBN and other activated cannabinoids Detects THC, THCA, CBD, CBDA and other acid and non acid cannabinoids
Cannot detect cannabinoid acids Can detect cannabinoid acids
Analysis does not produce significant waste Analysis produces significant solvent waste

Clearly, the current cannabis laboratory environment is unregulated so consumers have to be savvy. Knowing what questions to ask a prospective cannabis lab is key.  To help the process a group of laboratory service providers* from various states along with an international advisor compiled a list of 10 questions to ask a cannabis scientist. This can act as a quick reference guide for those looking for a qualified laboratory partner.

10 Questions to ask your cannabis scientist

1. What training or expertise do you have to be able to perform cannabis analysis?

2. Which cannabinoids do you test for? Do you have reliable reference standards for all of them?

3. How is CBN related to THC, and why is it important to test for it?

4. What kind of samples do you test (flowers, edibles, tincture)? Have you optimized your extraction and analysis protocol for each kind of sample?

5. What do you do with left-over samples?

6. Are you aware of acidic cannabinoids? In samples such as edibles and tincture they can be present at high levels. How do you deal with that?

7. What is your analytical methodology for testing cannabis (HPLC, GC, TLC, other)? What are the limitations of your selected method?

8. What is the average THC/CBD content your lab has measured?

9. Did your lab ever test the same cannabis twice, with very different results? What was the explanation for that, and what has been changed to prevent it from happening again?

10. Analytical methods need to be ‘validated’ before you can be sure they are fully reliable. Have you done this already, and how did you do this.  Did it include a third party?  If you didn’t do it yet, how can I be sure my results will be accurate?

*Contributors: Arno Hazekamp (Netherlands), Samantha Miller (Pure Analytics), Paula Morris (Medea Labs), Noel Palmer (Montana Botanical Analytics), Jeff Raber (The Werc Shop) and Eric Taylor (California Botanicals).  Collectively the ACS, Alliance for Cannabis Science.

Quick reference – http://www.freedomisgreen.com/10-questions-to-ask-your-cannabis-scientist/

Guest blog was submitted by Samantha Miller of Pure Analytics.

DISCLAIMER: The views and opinions expressed are those of the author and do not necessarily represent any University, business, affiliates or Freedom Is Green Media Group LLC. The information provided in this blog is not intended to diagnose or treat any disease.

Questions? Email science editor Jahan Marcu science(at)freedomisgreen.com


Dark Star Orchestra Performs Rare Acoustic Show

Dark Star Orchestra with freedomisgreen.com co-founder Jim Bissell (far right)

Just having performed two sold out shows in Reading, Pa and Tarrytown, NY, Dark Star Orchestra played again to another packed house for Mardi Gras at Mexicali Live in Teaneck, NJ last night.

It was a rare acoustic performance and the band played twenty nine songs lasting just over four hours with one set break.

“Where else can you listen to some of the best music on earth in the true spirit of the Grateful Dead?” proclaimed ‘Starhead’ Alex.

He’s right. There are GD cover bands that play the ‘Top 40, but if you were in attendance last night, you heard treasured classics Reuben and Cherise, My Brother Esau, and Mountains of the Moon.

Vocalist Lisa Mackey’s brilliant rendition of Bob Dylan’s Chimes of Freedom was spiritually moving and that was obvious to all those in attendance.  Complemented by Jeff Mattson on lead guitar, her strong vocals resonated throughout the crowd with the heartfelt justice the song deserved.

The Dark Star Orchestra Facebook Page is Here

 

Case Report Shows Dronabinol (Delta9-THC) can Help Autistic Children

dronabinol THC

Dr. René Kurz and Dr. Kurt Blaas published a case report documenting improvements in hyperactivity, lethargy, irritability, stereotypy and inappropriate speech in an autistic child administered dronabinol.*

The authors conclude that this study showed that the use of dronabinol may be able to reduce the symptoms of autism.

To date there have been no other reports of the use of cannabinoids in autism. The authors point to anecdotal data in internet blogs and discussion forums where there are many reports of parents who have tried THC for their autistic children, but without medical monitoring and inappropriate administration.

The abstract is below but you can read the full article here

Abstract

Objective: To evaluate the effectiveness of dronabinol (delta-9-THC) as supplementary therapy in
a child with autistic disorder.

Methods: A child who met the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders)
criteria for a diagnosis of autistic disorder and who took no other medication during the observation
time was included in an open and uncontrolled study. Symptom assessment was performed using the Aberrant Behavior Checklist (ABC) before and after six months of medical treatment.

Result: Compared to baseline, significant improvements were observed for hyperactivity, lethargy,
irritability, stereotypy and inappropriate speech at follow-up (p=0.043).

Conclusion: This study showed that the use of dronabinol may be able to reduce the symptoms of
autism.

Keywords: early infantile autism, autistic disorder, dronabinol, cannabinoid

This article can be downloaded, printed and distributed freely for any non-commercial purposes, provided the original work is properly cited (see copyright info below). Available online at www.cannabis-med.org

Read the full article here

Science Editor Jahan Marcu is currently investigating the pharmacology of cannabinoid receptors. Contact science { at } freedomisgreen.com

* dronabinol is marketed under the name Marinol.

DC, NY and East Coast residents pay highest prices for marijuana

8/31/2011 – Floatingsheep.org released their analysis of the underground marijuana market in the United States. The end result isn’t news to consumers: East Coast residents pay the most for an ounce of pot.

Wired magazine also featured a unique map (see below) that was created from the study data. It compares marijuana prices to the severity of laws. There were some other factors included into the equation, like the distance from Humbolt County, California.

The study centers on prices gathered directly from the public through anonymous online submissions. Thousands of individual reports were sent in through www.priceofweed.com.

Here is their rundown on the average cost of top-shelf marijuana:

Distribution of High Quality Observations by State

Connecticut          Reports= 124   Price = $426.20/oz

Delaware               Reports = 26    Price = $450.00/oz

D.C.                         Reports= 71      Price = $460.70/oz

Florida                  Reports=575    Price = $361.80/oz

Georgia                 Reports = 209  Price = $412.20/oz

Maine                    Reports =  57    Price = $360.00/oz

Maryland             Reports = 162   Price = $436.30/oz

Mass.                    Reports = 368    Price = $416.30/oz

New Hampshire Reports = 58      Price = $407.60/oz

New Jersey         Reports =  198   Price = $412.40/oz

New York            Reports = 876    Price = $416.90/oz

N. Carolina         Reports = 254    Price = $417.90/oz

Pennsylvania     Reports =  400   Price = $414.30/oz

Rhode Island     Reports =71       Price = $419.30/oz

S. Carolina          Reports =  98     Price = $399.00/oz

Vermont             Reports = 61      Price =$393.60/oz

Virginia               Reports =223    Price = $411.90/oz

West Virginia    Reports = 35     Price =$392.80/oz

Read the complete study here.

High Times Magazine has employed a similar method of collecting price information from readers for many years. The monthly “THMQ Pot Prices” column also offers a market analysis of different grades of marijuana and even individual strains.

Again, East Coast readers of HT mag are willing to exchange the most greenbacks for green flowers (with hints of reds, lavenders, oranges and purples). High Times July 2011 THMQ showed Chem Dog selling in New York for an astounding $560 per ounce.

While that was definitely the costliest bud found, many of the THMQs are close match for the floatingsheep.org prices.

Population density, thus simple demand, is a major factor to driving up prices on the East Coast. The severity of laws also tends to bump up the cost as distributors take a greater risk and pass that on to consumers.

Perhaps the most interesting trend for the cost of cannabis has been its stability over the last decade.  There have been moderate increases in the cost of all grades of marijuana. But there has been nothing of a cannabis price bubble compared to other consumer items, like housing, food or gasoline.

Some good news is that several data sources are showing a general decline in marijuana prices. For example the floatingsheep.org study showed that Oregonians pay an average of $255.80 per ounce for high-grade cannabis. So far, those kinds of price reductions have not reached the East Coast.

Chris Goldstein is a respected marijuana reform advocate. As a writer and radio broadcaster he has been covering cannabis news for over a decade. Questions?  [email protected]


CBD and other plant cannabinoids may fight Alzheimers’ disease

New research in The Journal of Molecular Pharmacology demonstrates that Cannabis compounds may be a promising treatment for Alzheimer’s disease. It may seem counter-intuitive that compounds from the Cannabis plant may preserve memory, however Cannabidiol (CBD) and other compounds on the plant have neuroprotective effects. CBD appears to inhibit the cells directly involved with the progression of the disease. Read the new study on cannabinoids and Alzheimer’s disease.