Another Study Confirms Anti-Cancer Effects of THC and CBD

Another Study Confirms Anti-Cancer Effects of THC and CBDby – Jahan Marcu, Science EditorExcerpt below- read in full at Jahan’s blog: The Philadelphia Medical Marijuana Examiner

Last year, the journal of Molecular Cancer Therapeutics published research demonstrating that combination’s of THC and CBD, the two most abundant cannabinoids on the plant, can lead to a greater-than-additive or synergistic inhibition of cancer growth. Now, nearly a year to the date, the journal has published another article studying the anti-cancer effects of THC and CBD. The new article takes the next steps towards getting this therapy in to the clinic by testing THC and CBD in animals along side a common brain tumor drug TMZ (temozolomide).The study was conducted in Spain, and the experiments analyzing the effects of cannabinoids were conducted with tumors or brain cancer cells from human samples and a tumor xenograft mouse model. A tumor xenograft model is basically a cancer that is induced into an animal that has a compromised immune system. This allows researchers to give a mouse a tumor consisting of human cells, thus a promising anti-cancer treatment can be tested on a human tumor in a more natural environment, than a petri dish.The plant cannabinoids used for this study were “kindly provided by GW pharmaceuticals.” THC and CBD were also provided as plant extracts or “botanical drug substances,” meaning they contained small amounts of other cannabinoids. Allowing these researchers to construct a custom anti-cancer, Sativex-like substance. Other synthetic cannabinoids such as SR141716A and SR144528 were donated by Sonafi-Aventis.In the figure provided it shows that THC and TMZ can drastically inhibit the size of tumor. The pictures on the graph are of tumors after 15 days of treatment.

Read in full at Jahan’s blog: The Philadelphia Medical Marijuana Examiner